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Inside the FDA’s Quiet Move to Weaken Drug Approval Standards

The Food and Drug Administration (FDA) is preparing to reduce the default number of clinical trials it will require to approve new drugs, a shift…

Dec 17, 2025

Terms and Conditions

MedShadow Does Not Provide Medical Advice. The contents of MedShadow.org and all affiliated social media postings, discussion groups and podcasts are under the management of…

Nov 12, 2025

Can I Take Prilosec with Levothyroxine?

If you experience frequent heartburn, you’ve likely considered taking an over-the-counter proton-pump inhibitor (PPI) like omeprazole (brand names include Prilosec OTC and Zegerid OTC). Some research suggests…

Aug 21, 2025

FDA SIDE EFFECTS UPDATE: Gabapentin and Pregabalin Withdrawal Risks

Welcome to the FDA Side Effects Update. This series is designed to keep you informed about the latest safety advisories and newly documented side effects…

Jun 17, 2025

What Is Addyi? The Controversy Behind the Drug Nicknamed the ‘Female Viagra’

[Editor's note: On December 15, 2025, the FDA extended its approval of Addyi to postmenopausal women under the age of 65. In making that decision,…

Jun 6, 2025

Is Benzoyl Peroxide Still Safe? What to Know About Acne Treatment Recalls

Acne impacts as many as 50 million Americans annually, and many rely on over-the-counter or prescription treatments containing benzoyl peroxide to control breakouts. First introduced in 1934,…

May 28, 2025

The PPI Debate: Are Heartburn Drugs Like Prilosec and Nexium Linked to Dementia?

Most of George Grossberg’s patients have lists of medications as long as his arm. So it takes the geriatric psychiatrist no small amount of time to…

May 9, 2025

Mission Critical Update: Medication Safety Updates from the FDA Delayed

For a few months now, our writer Katie Rowley has been making sense of the Food and Drug Administration’s (FDA) updates on drug safety for MedShadow readers…

Apr 24, 2025

Opinion: RFK’s “Radical Transparency” Looks More Like A Closed Door

When Robert F. Kennedy Jr., the newly appointed head of U.S. Health and Human Services (HHS), promised an era of “radical transparency” on February 13th, many…

Mar 13, 2025

INVESTIGATING GENERICS: Hundreds Of Drugs Remain On The Market After Fraudulent Trials

Hundreds of FDA-approved drugs on the market may have been approved based on fraudulent trials. This is according to a notice from the U.S. Food and Drug…

Oct 28, 2024

4 Science-Backed Lifestyle Changes for Hypertension Management

Managing your blood pressure (hypertension) is one of the best ways to improve your overall health and longevity. Heart disease remains the leading cause of death¹ of men…

May 3, 2024

The Side Effects of Wegovy and Ozempic

A well-known diabetes drug has gotten a lot more popular over the last two years. In June 2021, Wegovy, a new formulation of semaglutide, the…

Mar 19, 2024

Can I Take My Medicine or Supplement Before My Blood Test?

Fans of “Seinfeld,” the TV show still in reruns, will remember when Elaine failed a company drug test because she had a poppy-seed bagel an…

Sep 5, 2023

Could It Be My Medications?

Modern medications can be miracles that save us or our loved ones.  But they come with complexities.  No medicine goes straight to its desired target…

Jan 23, 2023

5 Meds That Mess With Digestion (Plus 1 Life-Saving Test)

Some of the most common drugs can mess with your digestion, leaving you backed up or making a run for it. Here’s how to cope.…

Mar 22, 2022

5 Common Drug Reactions That Affect the Skin

Drug Allergies Affecting the Skin are Common Of all the side effects that can result from the use of medication, drug allergies affecting the skin are…

Jan 31, 2021

9 Facts About Your Acne Drug, Isotretinoin

Accutane — The Drug That Cleared Severe Acne But Was Also Linked To Depression The drug that clears acne, but was also linked to depression,…

Nov 6, 2020

Flu Season … Wait Before Taking That Z-Pack!

Z-Pack and the Flu The flu season is heading straight towards us. I was taught that it takes a week to get over a cold…

Oct 23, 2013