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Diabetes

Learning You Have Type 2 Diabetes the Hard Way

“Long story short, I was diagnosed with type 2 diabetes in the emergency room. I don’t really remember what happened. I only remember a nurse struggling to put in an IV line. My A1c was a whopping 14 and was warned that if I didn’t take control of my life I would be a repeat customer.”

When Side Effects Prevail

Nearly one-third of all patients will stop taking a prescription medication without even telling their doctor. There are a variety of reasons people stop taking medications that have been prescribed for them. Sometimes they don’t think they need to take the medicine, or think it isn’t working. Maybe they’ve heard…

Diabetes Drug May Also Help Kidney Disease

A diabetes drug may also help people with kidney disease by reducing the risk of experiencing kidney failure. The drug, Invokana (canagliflozin), is known as an SGLT2 inhibitor. In a new study, published in the New England Journal of Medicine, patients with diabetes and chronic kidney disease taking Invokana and…

What You Should Know About Taking Diabetes Meds

Your doctor has just prescribed you a diabetes medication. Here’s how they work to reduce blood glucose levels and what to be aware of while taking them. At a recent visit to the doctor’s office, I had blood drawn for a number of lab tests, including ones to detect diabetes….

FDA Warns of Genital Infection Risk With Class of Diabetes Drugs

The FDA is warning that a rare genital infection may be linked to a class of diabetes medications. From March 2013 to May 2018, the agency said it received word of 12 cases of Fournier’s gangrene – a potentially life-threatening bacterial infection of tissue under the skin around the genitals…

For Those With Diabetes, A Good Diet Can Be Better Than Medicines

By Diane ArcherJustCareUSA.org A recent article in NEJM Catalyst describes a new disease management trial at Geisinger Health System. Geisinger is testing providing free food to patients with diabetes who were not eating a balanced diet, as a medicine. It recognizes that a good diet can be better than medicines…

How Do You Know Which Diabetes Drug Is Best for You?

The incidence of type 2 diabetes is rapidly rising, as has been well publicized in recent years. An estimated 30 million people in the US, or about 9.4% of the population, have it. That’s up from 2.5% in 1980. Some 1.5 million adults are newly diagnosed every year. An increasing…

Black-ish Hits a Sour Note When It Comes to Diabetes

The ‘Sugar Daddy’ episode is in ‘collaboration’ with Novo-Nordisk – maker of diabetes drugs – and minimizes the ways diet and exercise can help diabetics. Do you like the TV show black-ish? I do. It’s funny, and the acting is outstanding. But even better, every week the show uses its…

Side Effects Blamed for Fall-Off of Metformin Use by Type 2 Diabetics

An article in the journalDiabetes, Obesity and Metabolism reports that 30% of diabetic patients who are prescribed metformin do not take the medication because of its side effects. Researchers from the University of Surrey set out to see how likely patients were to take their medication by analyzing database information…

Diabetes Pill Shows Additional Weight-Loss Promise

An oral drug for type 2 diabetes worked just as well as the injectable version in controlling blood sugar and helping with weight loss. Researchers from the University of Leicester Diabetes Research Centre in England discovered that oral semaglutide, which is taken once daily, resulted in better glycemic control than…

Statin Use May Boost Diabetes Risk in Some People

People who are at high risk of developing type 2 diabetes may increase that risk by taking a statin medication over the long term. Statins are cholesterol-lowering medications, though they are also given to people thought to be susceptible to diabetes to help head off cardiovascular disease and to lower…

A Trail of Clues to a New Diabetes Drug

The real hope is to find a drug that lowers blood sugar, weight and cardiovascular risk. This drug comes close, but is it safe for everyone? Last week I sat on an FDA panel as the lone Consumer Rep to discuss and vote on an application for a diabetes drug,…

Young People on Antidepressants at Increased Risk of Developing Type 2 Diabetes

Researchers from the University of Maryland examined the medical claims of nearly 120,000 patients between the ages of 5 and 20 years old who were using antidepressants. The team compared incident cases of diabetes among the young patients using antidepressants — patients who didn’t discontinue the medications for more than…

Can Diabetics Train to Use Less Glucose-Lowering Medication?

A stringent program of diet and exercise did help study participants lower their meds. Could a less rigorous program work equally well? Many type 2 diabetics find that glucose-lowering medication is difficult to tolerate. These drugs have multiple potential adverse drug interactions, they are expensive, they cause discomfort and generally…

Diabetes Drug Lowers CV Events, but at Serious Cost: Amputation Risk

A new study demonstrates that a relatively new and popular diabetes drug, Invokana (canagliflozin), also has cardiovascular benefits, such as reducing the risk of heart attacks, but at a serious cost – an increased risk of leg and foot amputation. Conducted by Invokana’s manufacturer, Janssen Pharmaceutical, results showed that patients…

New Diabetes Drugs May Boost Ketoacidosis Risk

The newest class of diabetes drugs on the market may increase a patient’s risk for developing a serious complication of the disease that can potentially be fatal. Researchers found that type 2 diabetes patients taking SGLT2 inhibitors – which include Farxiga (dapagliflozin), Invokana (canagliflozin) and Jardiance (empagliflozin) – were twice…

Diabetes Drugs

If you’ve been diagnosed with type 2 diabetes, losing weight, exercising and changes in diet or exercise might be enough to keep your blood sugar in check. If it is not, your doctor is likely to prescribe medication. While insulin is among one of the first treatments a medical professional…

6 Dangers Unique to People with Diabetes

From alcohol, to over-the-counter meds and herbal supplements, find out what substances and scenarios people with diabetes need to be aware of. If you have diabetes, you probably know all about how food affects your blood sugar, including what, when, how often and how much you eat. Skipping meals, for…

Diabetes Drug Class Linked to Bile Duct and Gallbladder Disease

A popular class of drugs used to treat type 2 diabetes may increase the risk of bile duct and gallbladder disease. The class, GLP-1 (glucagon-like peptide 1) receptor agonists, is given via an injection and includes Byetta (exenatide), Victoza (liraglutide) and Trulicity (dulaglutide). Health records of more than 1.5 million…

Newer Diabetes Meds No Better Than Older, Cheaper Ones

People with diabetes have a multitude of drug options to keep their blood sugar in check from cheap generics that have been around for decades to newer drugs that are pricey to say the least. But the newer drugs are no better at cutting the risk of heart disease, stroke…

Risks Emerge for New Class of Diabetes Drugs

A new class of diabetes drugs that has been available for a little over three years have become immensely popular with doctors and patients, even though the pills have a host of adverse events and risks. The first SGLT2 (first sodium-glucose cotransporter-2) inhibitor to hit the market, back in 2013,…

Aggressive Diabetes Treatment May Harm Some Patients

Many people who have diabetes, particularly seniors, are so aggressively treated for the condition with many drugs that it may be putting them at risk for dangerously low blood sugar levels. Researchers examined data on more than 31,000 adults with type 2 diabetes. About 20% of those studied were considered…

Quick Hits: Amputation Risk With Diabetes Med, & More

People taking the diabetes medication Invokana may be at risk for leg and foot amputations. The FDA is alerting the public about interim safety results from an ongoing clinical trial that found an increase in the amputations, mostly affecting the toes, in patients taking Invokana (canagliflozin). The FDA has not…

Metformin Safer For Type 2 Diabetes Than Newer Drugs

Metformin, one of the most popular drugs prescribed to treat type 2 diabetes that has been available as a generic for many years, is safer for the heart than many newer -– and more expensive -– drugs, according to a new analysis. The findings, published in the Annals of Internal…

Blood Thinner, Certain Diabetes Drugs Are a Bad Combo

Taking the blood thinner warfarin at the same time as certain diabetes drugs increases the risk of hospitalization, a study from the University of Southern California warns. Researchers analyzed data from nearly 466,000 Medicare patients. They found that those who took warfarin along with the diabetes drugs glipizide or glimepiride…

New Diabetes Cases Dropping for First Time

Over the past 7 years, the number of new diabetes cases reported has dropped, and by a substantial number. According to the NYTimes, “The rate of new cases fell by about a fifth from 2008 to 2014, according to researchers at the Centers for Disease Control and Prevention, the first…

FDA Approves Tresiba

Novo Nordisk announced that the U.S. Food and Drug Administration (FDA) has approved Tresiba for the treatment of diabetes mellitus in adults after review of the class II resubmissions of the New Drug Application (NDA). Via Drugs.com. Posted September 25, 2015. –Alanna McCatty

FDA Says Certain Type 2 Diabetes Drugs Can Cause Serious Joint Pain

The U.S. Food and Drug Administration (FDA) said in a safety alert that some widely used treatments for Type 2 diabetes can cause severe and disabling joint pain, raising concerns for a big-selling class of drugs. The FDA alert applies to a category of pills known as DPP-IV inhibitors, which…

FDA Issues Warning on Common Diabetes Drugs

The FDA warned that a widely used newer class of type 2 diabetes drugs sold by AstraZeneca, Johnson & Johnson and Eli Lilly in partnership with Boehringer Ingleheim may lead to ketoacidosis, a serious condition where the body produces high levels of blood acids called ketones. Via Newsmax Health. Posted…

Diabetes Drug May Not Guard Against Pancreatic Cancer

A new study finds the diabetes drug metformin doesn’t help patients with a type of pancreatic cancer, as evidence formerly suggested. Researchers examined the medical records of 1,360 patients with pancreatic ductal adenocarcinoma, some of whom took metformin. The median number of survival days for those who didn’t take the…

AstraZeneca’s diabetes drug Onglyza may increase death rate -FDA

AstraZeneca Plc’s diabetes drug Onglyza may be associated with an increased rate of death, according to a preliminary review of data by the U.S. Food and Drug Administration (FDA). A trial of more than 16,000 patients known as SAVOR previously showed that patients taking Onglyza, also known as saxagliptin, had an…

Diabetes drugs may promote heart failure, study finds

According to a study reported in The Lancet Diabetes and Endocrinology, patients who manage type 2 diabetes with drugs that lower glucose or blood sugar may be at higher risk for heart failure. Results showed that 95,000 randomly selected patients who took new or more intensive blood sugar-lowering drugs, or…

The Dark Side of Diabetes Drugs

Many drugs used to treat diabetes are approved by the FDA using surrogate endpoints, causing serious side effects. Surrogate endpoints: If you think that sounds like medical mumbo jumbo, keep reading. For some people with diabetes, medications that were approved based on surrogate endpoints may lead to serious side effects….

Cancer Diagnosis Affects Adherence to Diabetes Drugs

A new study suggest that drop-offs in compliance with diabetes medication might negatively affect survival and could therefore partly explain the established higher cancer mortality seen among diabetes patients with worse glycemic control, according to the Netherlands Comprehensive Cancer Organization. Via Medscape Medical News. Posted January 29, 2015. –Alanna McCatty

Diabetes Drugs Turn Balancing Side Effects Into a Juggling Act

MedShadow.org reports on side effects, new drugs and recalls NEW YORK CITY, NY, October 30, 2014 – The diabetes epidemic continues to spread with the Center for Disease Control reporting that 29 million Americans have the disease, up from 26 million in 2010. Projections are that 1 in 3 people…

Diabetes Drugs: Balancing Side Effects

If some combination of losing weight, making dietary changes and exercising doesn’t help a diabetic achieve target blood sugar levels, a doctor will prescribe oral antidiabetic medications. With the increased prevalence in type 2 diabetes has come a vast increase in the number of drugs designed to manage the condition….

Light-activated drug could reduce side effects of diabetes medication

Diabetes drugs that promote the release of insulin from the pancreas can in some cases cause side effects due to their actions on other organs. To help create better drugs, researchers at Imperial College London and LMU Munichadapted an existing type of drug called a sulfonylurea so that it changes…

Attacking Type 2 Diabetes From a New Direction with Encouraging Results

New research shows promising evidence that a modified form of a different drug, niclosamide – which eliminate intestinal parasites – may hold the key to battling type 2 diabetes. Victor Shengkan Jin, an associate professor of pharmacology at Rutgers Robert Wood Johnson Medical School, found that niclosamide ethanolamine salt (NEN)…

Use of Metformin Tied to Risk of Low Thyroid Hormone Levels

In the latest study, researchers at McGill University in Montreal found that Metformin, a commonly used drug to treat type-2 diabetes, increases the risk of low thyroid-stimulating hormone level in patients with underactive thyroids. In this study, 74,300 patients were given either Metformin or sulfonylurea, over a 25-year study period. In…

Dear Pharmacist: Answer to “whys” benefit patients

“When you block the calcium-dependent membrane function in your gut with the drug metformin (used for diabetes), you lower vitamin B12 levels. A deficiency of B12 is well-documented. It can cause painful neuropathies. This answers the “why” question in case you have more numbness or pins and needles in your…

Antidepressant Use During Pregnancy May Lead to Childhood Obesity and Diabetes

According to new research, women who take antidepressants during pregnancy may be unknowingly predisposing their infants to type 2 diabetes and obesity later in life. Research demonstrated for the first time in an animal model that maternal use of a class of antidepressants called selective serotonin reuptake inhibitors (SSRIs) resulted…

Antidepressants could increase diabetes risk

The link might be coincidental, but a recent review of studies indicates that many people who use antidepressants go on to develop diabetes. NursingInPractice.org and several other sites reported on a University of Southampton (UK) review of 22 studies. Causation has not been established, but antidepressants cause weight gain which…

Weight Loss No Help for Heart in Diabetes

Dr. Sanjay Guptareports on a study that showed many benefits of losing weight even though improved heart health was not one of them. In a study, that seems flawed from our reading, the focus was to lower heart attacks in diabetics through weight loss. Since that direct correlation wasn’t established,…

Obesity as a side effect, not an enemy

I just saw a thought-provoking “TedTalks” by Peter Attia, MD, about diabetes and obesity. Please take time to watch it. I can’t do justice to it, but he is challenging the accepted thinking about weight, insulin and diabetes. We know insulin resistance leads to diabetes. We assume the overweight leads…