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Gout

Increased Death Risk Prompts Boxed Warning for Gout Drug

Doctors should avoid prescribing the popular gout drug Uloric (febuxostat) in favor of Zyloprim (allopurinol) since there is an increased risk of death associated with Uloric, according to an FDA warning. The FDA says its review of a postmarket trial of 6,000 patients comparing Uloric to Zyloprim found that Uloric…

What You Need to Know About Gout Treatments

Gout has a name-recognition problem. Even though its prevalence is increasing dramatically in the US, many physicians don’t recognize how serious the condition can be, says N. Lawrence Edwards, MD, a rheumatologist with University of Florida Health in Gainesville and chairman of the Gout & Uric Acid Education Society. (Editor’s…

Gout Drug Associated with Cardiovascular Risk

The gout drug Uloric (febuxostat) appears to have a higher rate of heart-related death when compared with another gout medication, according to a new FDA safety alert. Following Uloric’s approval in 2009, the FDA required its manufacturer, Takeda Pharmaceuticals, to conduct a postmarket safety trial because clinical trials indicated that…

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