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Parkinson's drugs
Acadia Pharmaceuticals is facing a Department of Justice probe over marketing practices related to its controversial Parkinson’s drug Nuplazid (pimavanserin). The investigation was disclosed in an SEC document and was first reported by CNN. In the filing, the company said it had received a civil investigative demand from the DOJ…
If patients taking a drug during a clinical trial experienced serious adverse events – including deaths – at twice the rate of those on placebo, you would think that drug wouldn’t get approved by the FDA. Yet that’s the case with the Parkinson’s drug Nuplazid (pimavanserin). And the FDA has…
Since Nuplazid launched in June 2016, the FDA has received more than 700 reports of deaths linked to it. The FDA should pull this drug from the market. The FDA should be vigilant of new drugs approved, but especially so for those that are approved under an expedited or accelerated…
Warnings about potential unusual side effects such as compulsive shopping or eating, and gambling should be placed on certain drugs that treat Parkinson’s disease,according to a consumer advocacy group. Public Citizen has filed a petition with the FDA asking the black box warnings – the strongest warning possible – should…
The FDA on Friday, April 29, granted approvalto the first drug ever to treat the hallucinations and delusions that are seen in as many as 40% of people with Parkinson’s disease. While Nuplazid(pimavanserin) certainly meets an unmet medical need for this population, some questions remain over whether the medication is more…
Levodopa is a widely used drug to treat stiffness, tremors and poor muscle control caused by Parkinson’s disease. However, the drug can also trigger uncontrolled movement — dyskinesia — which can significantly reduce a patient’s quality of life, according to researchers at Northwestern University School of Medicine. Via U.S. News…
There are 2 main categories of drugs for Parkinson’s Disease, and both have powerful side effects: levodopa, which makes many patients shaky with dyskinesia, and dopamine agonists, which can make turn people into gamblers, sex addicts or hit them with ‘sleep attacks’ — including when they’re driving. This is the…
Although there’s no cure for Parkinson’s Disease (PD), it’s not a death sentence. Despite the tremors, rigidity, fatigue and a potentially dramatic cycle of on and off periods in which one’s ability to move with ease is greatly affected, it is possible to live a fairly normal life — with…
An analysis of FDA side-effects reports by healthcare informatics firm AdverseEvents has uncovered potentially worrisome signals for two of Novartis’ meds, Exelon for Parkinson’s and Alzheimer’s disease, and Stalevo for Parkinson’s disease. AdverseEvents reported 11 cases of cardiopulmonary failure, 5 cases of acute respiratory failure and almost 1,200 deaths in…
Previously, studies have found that the cholesterol-lowering medications statins may offer protective benefits against Parkinson’s disease. However, a new study led by researchers at Penn State College of Medicine and the National Institute of Environmental Health Sciences found an increased long-term risk of Parkinson’s disease among statin users. Via Medical…
