Malaria Test Predicts Treatment Side Effects

New Malaria Test Can Help Predict Serious Side Effects of Treatment
New Malaria Test Can Help Predict Serious Side Effects of Treatment

Researchers at Paris Descartes University have discovered a way to predict which malaria patients will suffer from a serious — often fatal — side-effect of the usual treatment. And the cost will be relatively low, because the researchers found they could get the needed results by repurposing an existing test.

Most patients recover from malaria after taking artemisinin artesunate, but a small number develop post-artesunate delayed haemolysis (PADH) within a month of treatment. PADH is a form of anemia that can lead to kidney failure and death.

Until now, clinicians were unable to pinpoint who might develop PADH. But in their test, the researchers found they could use an existing malaria kit called BinaxNOW with significantly accurate results in detecting PADH.

Pierre Buffet, head of the RBC (red blood cell) research team at the faculty of medicine, Paris Descartes University, reported that the modified diagnostic test predicted PADH with 89% sensitivity and 73% specificity.

In 2015, there were roughly 212 million malaria cases and an estimated 429,000 malaria deaths, according to the World Health Organization.

Instead of monitoring the malaria patients for 28-days to see if the side effects develop, Buffet says that the new plan is to use the test three days after the start of treatment.

“Our first step is to perform a multisite study to confirm predictive thresholds and impact, predominantly in African children,” Buffet told SciDev.net.

DISCLAIMER: MedShadow provides information and resources related to medications, their effects, and potential side effects. However, it is important to note that we are not a substitute for professional medical advice, diagnosis, or treatment. The content on our site is intended for educational and informational purposes only. Individuals dealing with medical conditions or symptoms should seek guidance from a licensed healthcare professional, such as a physician or pharmacist, who can provide personalized medical advice tailored to their specific circumstances.

While we strive to ensure the accuracy and reliability of the information presented on MedShadow, we cannot guarantee its completeness or suitability for any particular individual's medical needs. Therefore, we strongly encourage users to consult with qualified healthcare professionals regarding any health-related concerns or decisions. By accessing and using MedShadow, you acknowledge and agree that the information provided on the site is not a substitute for professional medical advice and that you should always consult with a qualified healthcare provider for any medical concerns.

Was This Article Helpful?

Show Comments (0)
0 0 votes
Article Rating
Notify of
Inline Feedbacks
View all comments
Would love your thoughts, please comment.x