We normally focus on long-term effects of medicines, but why hold back on good news? NYTimes reported on a study today that measured exercise and dementia. The study ran for nearly 40 years with 19k+ participants. Those who exercised the most (top 20%) had the fewest diagnoses of dementia. Those who exercised least (bottom 20%) were much more likely to get dementia. We call avoiding dementia a long-term positive effect. The study was published in the Annals of Internal Medicine and did not mention who sponsored it … Richard Simmons perhaps?