Many Older Patients End Up Using Benzodiazepines Long Term

Although tranquilizer drugs known as benzodiazepines are only meant for short-term use, about one-third of older adults who get a prescription for them end up continuing on them for the long term.

Researchers interviewed 576 older adults that were newly prescribed a benzodiazepine. Common benzodiazepines are Valium (diazepam), Xanax (alprazolam) and Klonopin (clonazepam). Participants were also asked questions relating to depression, anxiety, sleep quality and pain.

Results, published in JAMA Internal Medicine, found that experiencing poor sleep quality was most associated with long-term benzodiazepine use. Also, white patients and those patients prescribed pills for a longer number of days at the outset were more likely to end up using benzodiazepines for the long term.

Researchers also noted that long-term benzodiazepine patients were prescribed, on average, 8 months’ worth of the medication. Benzodiazepines are found on the Beers Criteria, a list compiled by the American Geriatrics Association of medications that are potentially inappropriate for seniors. The group says that benzodiazepines drugs can increase the risk for falls and mental decline, and its effects often last longer than expected.

“For new benzodiazepine users, prescribers should ‘begin with the end in mind’ and immediately engage patients in discussion regarding the expected (brief) length of treatment, particularly when prescribed for insomnia,” the researchers concluded.


Jonathan Block

Jonathan Block

Jonathan Block is an associate editor at BioCentury, which provides news and information about the biotechnology and pharmaceutical industries. Prior to joining BioCentury in 2019, Jonathan worked for MedShadow as content editor. He has been an editor and writer for multiple pharmaceutical, health and medical publications, including The Pink Sheet, Modern Healthcare, Health Plan Week and Psychiatry Advisor. He holds a BA from Tufts University and is earning an MPH with a focus on health policy from the CUNY Graduate School of Public Health & Health Policy.


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