MedShadow Features

The Fosamax Case Before the Supreme Court

January 14, 2019

In the fall of 2018, MedShadow Foundation and three past FDA executives contributed an amici curiae brief to the Supreme Court in the case of Merck vs. Albrecht.

The Supreme Court heard the case on Monday, January 7, 2019. The ruling is expected to be published in May.

Continue Reading →

5 Non-Pharmacological Treatments for Depression

January 14, 2019
5 Non-Pharmacological Treatments for Depression

Although antidepressants are a first-line treatment for depression, many people don’t respond well to them. But there are non-drug options that may work.

5 Things to Know About Ketamine for Depression

January 3, 2019
5 Things to Know About Ketamine for Depression

The anesthetic ketamine is increasingly being used off-label for treatment-resistant depression. The drug seems to work rapidly, but its benefits may be short-lived and long-term side effects are unknown.

Did Merck Circumvent Its Duty To Warn on ‘Fosamax Fractures’?

December 18, 2018
What Was Merck's Duty to Warn on Fosamax Fractures?

At issue is how Merck dealt with updating Fosamax’s label when it became aware of spontaneous fractures. MedShadow filed an amicus curiae brief in the case.

Can a Placebo Pill Treat a Medical Condition?

December 17, 2018
Can a Placebo Pill Treat a Medical Condition?

Some patients are finding relief without side effects when they take pills that are actually marketed as a placebo. Small trials have backed them up, but many doctors are skeptical.

Is Your Child on Multiple Meds? He May Be at Increased Risk for Adverse Events

December 10, 2018
Is Your Child on Multiple Meds? They May Be at Increased Risk for Adverse Events

Abnormal heart rhythms, depressive symptoms and even suicidal ideation have been seen with drug-drug interactions in children

Is Common MRI Contrast Dye Safe? What You Need to Know

December 3, 2018
Is Common MRI Contrast Dye Safe?: What You Need to Know

Gadolinium-based contrast agents can linger in the body years after an MRI.

Pros & Cons: Long-Acting Reversible Contraceptives

November 26, 2018
Pros & Cons: Long-Acting Reversible Contraceptives

LARCs such as IUDs and rod implants in the arm (Nexplanon) are popular because they are very effective. There are steps to take to minimize side effects.

Can Bisphosphonates Stop Breast Cancer from Spreading to Bones?

November 19, 2018
Bisphosphonates for Breast Cancer: Can It Stop Cancer Spread to Bones?

Cancer spreading to bones is common in breast cancer. Bisphosphonates, drugs used to treat osteoporosis, may help stop the metastasis, but is it worth it?

What You Need to Know About Gout Treatments

November 12, 2018
What You Need to Know About Gout Treatments

Gout is one of the most painful types of arthritis. While medications can help, lifestyle and dietary changes can minimize flare-ups and the use of drugs.

Can Artificial Intelligence Predict Drug Side Effects?

November 5, 2018
Can Artificial Intelligence Predict Drug Side Effects?

With many people on multiple medications, it’s difficult to know what adverse events can occur. An experimental system called Decagon is aiming to change that.

Drinking and Drugs: How Alcohol Can Mess With Your Meds

October 22, 2018
Drinking and Drugs: How Alcohol Can Mess With Your Meds

Many medications have a warning not to mix with alcohol because of serious side effects. What drugs can have the most dangerous interactions with alcohol?