Targeted Therapies Could Reduce Side Effects

Treatments that are applied to non-target areas within the body can lead to unnecessary side effects and cause debilitating symptoms. In some instances, this can prompt patients to stop their course of treatment early. In an effort to combat this and limit side effects, researchers are in the process of designing and developing light-activated small molecules that can be switched on and off in the body.

The treatments would be designed to target and penetrate a specific area, according to an article published in Chemical & Engineering News. A good example of this would be where doctors turn on chemotherapy agents to kill tumors and turn on antibiotics to wipe out bacteria within the body.

Although photoswitchable (also known as photodynamic) therapies aren’t new, they are still in the process of being developed and have some drawbacks. For instance, certain therapies are switched on with UV light, but wavelengths don’t penetrate very far through the skin and can cause mutations.

Additionally, the treatment may face some pushback when it comes to obtaining regulatory approvals because it is very complex. Despite some of the anticipated obstacles, chemists are moving forward with their research in hope that more selective therapies could be used to treat patients in need.


Alanna McCatty

Alanna McCatty

Alanna McCatty is founder and CEO of McCatty Scholars, an organization that devises and implements financial literacy programs for students to combat the nationwide issue of the loss of educational opportunity due to the ramifications of burdensome student debt. At MedShadow, she reports on new findings and research on the side effects of prescription drugs. She is a graduate of Pace University.


Did you find this article helpful?


Latest News

FDA Recalls Metformin and NP Thyroid

FDA Recalls Metformin and NP Thyroid

The FDA has issued a recall of two drugs–NP Thyroid and Metformin–after testing revealed that they weren’t up to code. Read more below, and if you’re taking either medication, please be sure to contact your doctor for how to continue treatment responsibly.  NP Thyroid Recalled Thirteen lots of NP Thyroid,…

Can Convalescent Plasma Treat COVID-19 Patients?

Can Convalescent Plasma Treat COVID-19 Patients?

One of the most promising treatments for COVID-19 is convalescent plasma, a component of blood. People who have been infected with the virus and are now healthy have developed COVID-19-fighting antibodies, which, the theory is, can be given to people currently sick with COVID-19 so that those antibodies can boost…

  • Advertisement