Targeted Therapies Could Reduce Side Effects

Treatments that are applied to non-target areas within the body can lead to unnecessary side effects and cause debilitating symptoms. In some instances, this can prompt patients to stop their course of treatment early. In an effort to combat this and limit side effects, researchers are in the process of designing and developing light-activated small molecules that can be switched on and off in the body.

The treatments would be designed to target and penetrate a specific area, according to an article published in Chemical & Engineering News. A good example of this would be where doctors turn on chemotherapy agents to kill tumors and turn on antibiotics to wipe out bacteria within the body.

Although photoswitchable (also known as photodynamic) therapies aren’t new, they are still in the process of being developed and have some drawbacks. For instance, certain therapies are switched on with UV light, but wavelengths don’t penetrate very far through the skin and can cause mutations.

Additionally, the treatment may face some pushback when it comes to obtaining regulatory approvals because it is very complex. Despite some of the anticipated obstacles, chemists are moving forward with their research in hope that more selective therapies could be used to treat patients in need.


Alanna M.

Alanna M. is a graduate of Pace University.


Did you find this article helpful?


Subscribe
Notify of
guest
0 Comments
Inline Feedbacks
View all comments

Latest News

Covid-19: Side Effects of Trump’s Treatments

Covid-19: Side Effects of Trump’s Treatments

President Donald Trump announced (via Twitter, of course) what some considered unthinkable, and others considered inevitable — that he had tested positive for Covid-19. Over the weekend, he received various treatments  — supplements like vitamin D, zinc and melatonin, an experimental antibody combination, an antiviral drug and a powerful anti-inflammatory…

Un-Sheltering Tips for Your Health and Immune System

Un-Sheltering Tips for Your Health and Immune System

As we all emerge from our bubbles of limited contact with others, we are walking straight into the double whammy of flu season and COVID-19 germs. Can your body fight off exposure to the flu and COVID? Your immune system feeds off the basics of life — sleep, movement, food…