Antidepressants at Normal Doses Linked to First-Time Seizures

During the assessment period of a study spanning from 1998 to 2012, investigators at the University of Basel, in Switzerland, found an increased risk for first-time seizures in patients being treated for depression. Out of the 8.7 million patients, 619 of the151,005 that were diagnosed with depression had a first-time seizure. Incidence rates of seizures tended to be higher in users of SSRIs, SNRIs, or other antidepressants than in users of tricyclic antidepressants (TCAs) or nonusers of antidepressants. Via Medscape. Posted April 6, 2015.