The Food and Drug Administration (FDA) has approved a supplemental New Drug Application for Xenical (obesity management drug) regarding new drug interactions and adverse reaction updates to its labeling. Xenical is indicated for obesity management including weight loss and weight maintenance when used in conjunction with a reduced-calorie diet. The product labeling has been updated to include a possible drug interaction with amiodarone (treats life-threatening heart rhythm problems). Via MPR. Posted August 17, 2015.