UMARY Hyaluronic Acid Supplement Recalled for Contamination

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<p>A company called MXBBB is <a href="https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/mxbbb-issues-voluntary-nationwide-recall-umary-acid-hyaluronic-due-presence-diclofenac-and?utm_medium=email&utm_source=govdelivery" target="_blank" rel="noreferrer noopener">voluntarily recalling</a> one lot (or batch) of its product, UMARY hyaluronic acid tablets, sold on Amazon. The lot was contaminated with two drugs: dicloflenac (a prescription non-steroidal anti-inflammatory painkiller) and omeprazole (a proton pump inhibitor to prevent acid reflux).</p>
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<p>The universal product code (UPC) of the contaminated supplements is 7502265120323.</p>
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<p>The Lot number is 24183 and the expiration date is 07/01/28.</p>
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<h2 class="wp-block-heading" id="h.94srlbhr3rx7">Supplement Tainted with NSAID and Acid Reflux Drugs</h2>
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<p>Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) similar to ibuprofen. In the U.S., <a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/019201s048lbl.pdf" target="_blank" rel="noreferrer noopener">oral tablets require a prescription</a>, but topical creams containing the ingredient are available over-the-counter (OTC). While diclofenac works similarly to other NSAIDs, such as ibuprofen, researchers have found that it may <a href="https://www.bmj.com/content/362/bmj.k3426" target="_blank" rel="noreferrer noopener">raise the risk of cardiovascular problems</a>.</p>
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<p>To limit the risk of side effects, NSAIDs should be used sparingly and in the short term. However, unknowingly taking a daily supplement that contains a hidden NSAID can lead to overuse, especially if you also take another NSAID separately. Taking <a href="https://medshadow.org/nsaids/" target="_blank" rel="noreferrer noopener">NSAIDs</a> too frequently or in high doses can <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC10156439/" target="_blank" rel="noreferrer noopener">damage your digestive system</a>.</p>
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<p>Omeprazole is the generic form of a common OTC medication, Prilosec. If you take it daily over a longer period of time, you may have <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC11122117/#:~:text=PPIs%20are%20also%20widely%20used,increase%20in%20gastric%20acid%20production." target="_blank" rel="noreferrer noopener">rebound symptoms of acid reflux</a> when you try to stop taking it. The drug could also mask existing issues, so you might not notice symptoms of acid reflux, ulcers, or even stomach cancer. Omeprazole can make it harder for your body to absorb <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC9577826/" target="_blank" rel="noreferrer noopener">vitamins, such as vitamin B12</a>, which is important for building DNA. A B12 deficiency can cause <a href="https://www.ncbi.nlm.nih.gov/books/NBK441923/" target="_blank" rel="noreferrer noopener">anemia and neurological symptoms, such as problems with balance and memory</a>.</p>
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<p>Lastly, both diclofenac and omeprazole can interact with other medications you may be taking, rendering them less effective or even making them more potent.</p>
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<p>Some medications that interact with diclofenac include:</p>
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<ul class="wp-block-list"><!-- wp:list-item -->
<li><a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/019201s048lbl.pdf" target="_blank" rel="noreferrer noopener">Voriconazole</a></li>
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<li><a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/019201s048lbl.pdf" target="_blank" rel="noreferrer noopener">Aspirin</a></li>
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<li><a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/019201s048lbl.pdf" target="_blank" rel="noreferrer noopener">ACE Inhibitors</a></li>
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<li><a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/019201s048lbl.pdf" target="_blank" rel="noreferrer noopener">Angiotensin Receptor Blockers</a></li>
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<li><a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/019201s048lbl.pdf" target="_blank" rel="noreferrer noopener">Beta-Blockers</a></li>
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<li><a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/019201s048lbl.pdf" target="_blank" rel="noreferrer noopener">Diuretics</a></li>
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<li><a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/019201s048lbl.pdf" target="_blank" rel="noreferrer noopener">Digoxin</a></li>
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<li><a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/019201s048lbl.pdf" target="_blank" rel="noreferrer noopener">Lithium</a></li>
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<li><a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/019201s048lbl.pdf" target="_blank" rel="noreferrer noopener">Methotrexate</a></li>
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<li><a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/019201s048lbl.pdf" target="_blank" rel="noreferrer noopener">Cyclosporin</a></li>
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<li><a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/019201s048lbl.pdf" target="_blank" rel="noreferrer noopener">NSAIDs and Salicylates</a></li>
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<li><a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/019201s048lbl.pdf" target="_blank" rel="noreferrer noopener">Pemetrexed</a></li>
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<p>Some medications that interact with omeprazole include:</p>
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<ul class="wp-block-list"><!-- wp:list-item -->
<li><a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/019810s096lbl.pdf" target="_blank" rel="noreferrer noopener">Atazanavir and nelfinavir</a></li>
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<li><a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/019810s096lbl.pdf" target="_blank" rel="noreferrer noopener">Saquinavir</a></li>
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<li><a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/019810s096lbl.pdf" target="_blank" rel="noreferrer noopener">Digoxin</a></li>
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<li><a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/019810s096lbl.pdf" target="_blank" rel="noreferrer noopener">Clopidogrel</a></li>
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<li><a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/019810s096lbl.pdf" target="_blank" rel="noreferrer noopener">Cilostazol</a></li>
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<li><a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/019810s096lbl.pdf" target="_blank" rel="noreferrer noopener">Diazepam</a></li>
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<li><a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/019810s096lbl.pdf" target="_blank" rel="noreferrer noopener">Warfarin</a></li>
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<li><a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/019810s096lbl.pdf" target="_blank" rel="noreferrer noopener">Phenytoin</a></li>
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<li><a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/019810s096lbl.pdf" target="_blank" rel="noreferrer noopener">Cyclosporine</a></li>
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<li><a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/019810s096lbl.pdf" target="_blank" rel="noreferrer noopener">Disulfiram</a></li>
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<li><a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/019810s096lbl.pdf" target="_blank" rel="noreferrer noopener">Benzodiazepines</a></li>
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<li><a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/019810s096lbl.pdf" target="_blank" rel="noreferrer noopener">Tacrolimus</a></li>
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<li><a href="https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/019810s096lbl.pdf" target="_blank" rel="noreferrer noopener">Methotrexate</a></li>
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<h2 class="wp-block-heading" id="h.rgyeeeigetpj">How to Choose Safe Hyaluronic Acid Supplements</h2>
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<p>One way to reduce your risk of contaminated supplements is to <a href="https://medshadow.org/do-i-need-vitamin-supplements/#How_to_Choose_a_Supplement" target="_blank" rel="noreferrer noopener">check the label</a> for a certification that the supplement has been tested by a third party. Groups like the <a href="https://www.nsf.org/consumer-resources/articles/supplement-vitamin-certification" target="_blank" rel="noreferrer noopener">National Science Foundation (NSF)</a> or the <a href="https://www.usp.org/" target="_blank" rel="noreferrer noopener">United States Pharmacopeia</a> (USP) test supplements to confirm that they contain the products listed on the label and are free from unsafe levels of contaminants.</p>
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<p>While helpful for ingredient purity, these tests do not prove that the supplement is effective in improving any symptoms or quality of life. Always be sure to discuss any supplements you take with your healthcare provider to be sure that they are right for you and that they won’t interfere with any other treatments you may be using.</p>
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