Yeast Infection Drug, Diflucan, May Boost Miscarriage Risk

The FDA has issued a safety miscarriage alert recommending that women who are pregnant or are seeking to get pregnant avoid taking the vaginal yeast infection drug Diflucan (fluconazole).

The FDA is evaluating a study from Denmark that found reports of abnormalities in babies and miscarriage at birth whose mothers took as few as 1 to 2 doses of oral fluconazole (Diflucan)  at 150 mg. Previously, abnormalities had only been seen at higher doses (400-800 mg) for longer periods of time.

“Until FDA’s review is complete and more is understood about this study and other available data, FDA advises caution in prescribing of oral fluconazole in pregnancy,” the FDA said in a statement.

The current label for the antifungal med states that no study indicates an increased risk of pregnancy problems in women who take a single 150mg dose.

The Centers for Disease Control and Prevention also recommends that pregnant women use only antifungal creams, not oral meds, during pregnancy for yeast infections.

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