WELCOME TO MEDSHADOW. WE'VE UPDATED OUR LOOK!

Many Clinical Trials Often Absent From Journals

Clinical trial results are almost always listed in government sources, but many never make it into published literature, where they would have much greater exposure. The authors of a new research letter, published in JAMA Internal Medicine, noted that the exclusion of certain clinical trial results, which provide scientific data on a drug, leaves “a distorted body of public evidence.”

In order to assess the availability of clinical trial results in the public domain, researchers evaluated the availability of results in PubMed-cited publications and/or results posted in Clinicaltrials.gov.

The study consisted of 329 trials studying 86 drugs and representing 96 unique sponsor-drug-condition trial sets.

The results found that Clinicaltrials.gov consisted of nearly one-quarter of sampled drug trials and more than one-tenth of sampled sponsor-drug-condition trial sets. However, results remain unavailable in Clinicaltrials.gov or PubMed 7 or more years after study completion for nearly one-quarter of sampled drug trials and more than one-tenth of sampled sponsor-drug-condition trial sets.

“Systematic reviewers who rely entirely on literature searches are at risk of missing relevant evidence,” the authors wrote.

DISCLAIMER: MedShadow provides information and resources related to medications, their effects, and potential side effects. However, it is important to note that we are not a substitute for professional medical advice, diagnosis, or treatment. The content on our site is intended for educational and informational purposes only. Individuals dealing with medical conditions or symptoms should seek guidance from a licensed healthcare professional, such as a physician or pharmacist, who can provide personalized medical advice tailored to their specific circumstances.

While we strive to ensure the accuracy and reliability of the information presented on MedShadow, we cannot guarantee its completeness or suitability for any particular individual's medical needs. Therefore, we strongly encourage users to consult with qualified healthcare professionals regarding any health-related concerns or decisions. By accessing and using MedShadow, you acknowledge and agree that the information provided on the site is not a substitute for professional medical advice and that you should always consult with a qualified healthcare provider for any medical concerns.

Was This Article Helpful?

Show Comments (0)
0 0 votes
Article Rating
Subscribe
Notify of
guest
0 Comments
Inline Feedbacks
View all comments
0
Would love your thoughts, please comment.x