What I Wish More People Knew About ‘Safe’ Over-the-Counter Headache Medications
OTC painkillers are widely seen as safe. But frequent, unsupervised use can sometimes make chronic pain harder to treat
Jan 22, 2026
Noor F. Shaik, M.D., Ph.D., is a neurology resident physician in Philadelphia, Pennsylvania. She has published academic research and patient-facing articles on the prevention of and recovery after neurologic injuries. The opinions expressed in her articles do not necessarily represent those of the University of Pennsylvania Health System or the Perelman School of Medicine.
OTC painkillers are widely seen as safe. But frequent, unsupervised use can sometimes make chronic pain harder to treat
Jan 22, 2026We think it’s invaluable — and hope you agree. Our work is made possible by donations from readers like you.
We think it’s invaluable — and hope you agree. Our journalism is made possible by donations from readers like you.
As a nonprofit, we don’t take a dime from pharmaceutical or supplement companies. That means we can report on the benefits, risks, and alternatives to prescription and over-the-counter drugs free from corporate pressure or influence.