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A ranking of the most prescribed drugs in the U.S.

These are the medications most commonly prescribed to Americans. This list will be routinely updated as new data becomes available.

Atorvastatin

80.72 DDD/1000 pop/day

Rosuvastatin

77.95 DDD/1000 pop/day

Amlodipine

57.81 DDD/1000 pop/day

Perindopril

56.60 DDD/1000 pop/day

Telmisartan

36.14 DDD/1000 pop/day

Candesartan

36.13 DDD/1000 pop/day

Sertraline

30.11 DDD/1000 pop/day

Escitalopram

28.31 DDD/1000 pop/day

Metformin

28.25 DDD/1000 pop/day

Irbesartan

27.66 DDD/1000 pop/day

Source: ClinCalc.com for 2023

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What is Unbiased Drug-Safety Journalism Worth to You?

We think it’s invaluable — and hope you agree. Our journalism is made possible by donations from readers like you.

As a nonprofit, we don’t take a dime from pharmaceutical or supplement companies. That means we can report on the benefits, risks, and alternatives to prescription and over-the-counter drugs free from corporate pressure or influence.

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